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. 2014 Sep 2;42(17):11218–11232. doi: 10.1093/nar/gku782

Table 3. DNA binding affinity.

KD (μM) Rmax X2 (10−4)
MBD4MBD-mCpG 6.4 ± 1.5 0.74 34
MBD4MBD-TpG 11.5 ± 1.2 0.59 2.3
MBD4MBD-CpG 17.2 ± 2.0 0.91 3.5
MBD4MBD-hmCpG 14.2 ± 1.9 0.72 3.9
MBD4MBD(Y109F)-mCpG 7.9 ± 1.6 0.63 14
MBD4MBD(Y109F)-TpG 14.0 ± 1.4 0.51 1.0
MBD4MBD(Y109F)-CpG 19.6 ± 3.5 0.76 3.5
MBD4MBD(Y109F)-hmCpG 16.0 ± 3.0 0.59 3.4