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. 2014 Aug 7;289(38):26554–26565. doi: 10.1074/jbc.M114.589754

TABLE 1.

Proliferation rates in the continuous presence of rapamycin can quantitatively explain the times-to-recovery from rapamycin treatment

Comparison of the calculated initial slopes of the time-to-recovery data for WT and ego1Δ cultures derived from Fig. 1E but re-plotted as a function of log2 of rapamycin concentration and the experimentally determined doubling times of WT and ego1Δ cells determined in the continuous presence of rapamycin (20 ng/ml) and on the same day. Results are shown means ± S.D.

Strain Initial slope of recovery time vs. log2 of rapamycin concentration (hours), data from Fig. 1E Observed doubling time in the constant presence of rapamycin (20 ng/ml) (hours)
WT 6.85 ± 2.02 5.32 ± 0.17
ego1Δ 22.25 ± 1.22 23.79 ± 5.51