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SOCS3 and IRTyr-960 are reduced by pioglitazone. All work was done in REC and Müller cells left untreated (NT) or treated with pioglitazone. A and B, data in REC; C and D, Müller cell data. Data show that pioglitazone (PIO) reduced SOCS3 and IRTyr-960 in both cell types. *, p < 0.05 versus normal glucose (NG) untreated; #, p < 0.05 versus high glucose (HG) untreated. Data are mean ± S.E. (error bars); n = 4 for all treatments. A.U., arbitrary units.
