PPARγ activity is increased in REC and Müller cells after pioglitazone. For both REC and Müller cells, cells were grown in normal glucose (NG) or high glucose (HG). For REC, cells were treated with 25 μm pioglitazone (PIO), whereas Müller cells were untreated (NT) or treated with 25 or 50 μm pioglitazone. *, p < 0.05 versus normal glucose untreated; #, p < 0.05 versus high glucose untreated. Data are mean ± S.E. n = 4 for all treatments.