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. 2013 Nov 19;32(1):94. doi: 10.1186/1756-9966-32-94

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Copyright © 2013 Casadio et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Prognostic algorithm with the three significant genes (GSTP1, HIC1 and RASSF1). Sensitivity was evaluated as the number of recurrent tumors with unmethylated HIC1, RASSF1, GSTP1 relative to the total number of recurrent tumors analyzed. Specificity was evaluated as the number of non recurrent tumors with methylated phenotype relative to the total number of non recurrent tumors analyzed. Overall accuracy was calculated as the number of correctly classified tumors relative to the total number of analyzed tumors.