Table 5.
Family | Gender | Autism diagnosis | Type of seizure b | Risk factor of ASD and/or epilepsy |
---|---|---|---|---|
AU0025 |
M |
Autism |
Partial |
Mitochondrial disorder, mild tonsillectomy (premature puberty) |
|
M |
Autism |
Multiple |
No risk reported |
|
F |
Unaffected |
No seizure |
Unknown |
AU0051 |
M |
Autism |
Absence |
No risk reported |
|
M |
Autism |
Absence |
Agenesis of corpus callosum |
AU0123 |
F |
Autism |
Partial |
Prematurityc/pre- or perinatal insult |
|
M |
Autism |
Multiple |
Unknown |
|
F |
Unaffected |
No seizure |
Unknown |
AU0176 |
F |
Autism |
Partial |
No risk reported |
|
M |
Autism |
Partial |
No risk reported |
|
M |
Unaffected |
No seizure |
Unknown |
|
F |
Unaffected |
No seizure |
Unknown |
AU0275 |
M |
Autism |
Multiple |
No risk reported |
|
M |
Autism |
Not indicated |
Unknown |
|
F |
Unaffected |
No seizure |
Unknown |
|
F |
Unaffected |
No seizure |
Unknown |
AU0461 |
M |
Autism |
Generalized |
No risk reported |
|
M |
Autism |
Generalized |
Unknown |
AU0548 |
F |
Autism |
Absence |
No risk reported |
|
M |
Autism |
Not indicated |
No risk reported |
|
F |
Unaffected |
No seizure |
Unknown |
AU0731 |
M |
Autism |
Generalized |
Prematurityc/pre- or perinatal insult |
|
M |
PDD-NOS |
Not indicated |
Unknown |
AU0765 |
M |
Autism |
Absence |
Unknown |
|
F |
PDD-NOS |
Not indicated |
t(2;9)(p13;q34.3) |
|
M |
Unaffected |
No seizure |
Unknown |
AU0922 |
M |
Autism |
Partial |
No risk reported |
|
F |
Autism |
Partial |
Unknown |
AU1208 |
M |
Autism |
Multiple |
15q11–13 duplication |
M | Autism | Absence | Unknown |
aFrom the 154 families included in the co-segregation analysis, the families with ASD children and without epilepsy are not detailed in this table; bnot indicated means that the type of seizures was not given in the AGRE database, although the patient exhibits epilepsy; cdefined as delivery before 35 weeks of gestational age for single births or before 33 weeks of gestational age for twin births. AGRE, Autism Genetic Resource Exchange; ASD, autism spectrum disorders; PDD-NOS, pervasive developmental disorder-not otherwise specified.