Table 1. MAT Binding Affinities of Top VS Hit Compounds.

	Ki (nM)
	SERT	DAT	NET	selectivity ratio SERT/DAT/NET
TN-01	1029 ± 81	3058 ± 403a,d	613 ± 162b,e	2:5:1
TN-05	668 ± 41	>20 000	323 ± 53c,d	2:>62:1
TN-06	>20 000	15 740 ± 2787	841 ± 225c,e	24:19:1
TN-13	12 600 ± 2122	780 ± 78a,e	215 ± 55c,e	58:4:1

^aSERT vs DAT.

^bDAT vs NET.

^cSERT vs NET.

^dp < 0.005.

^ep < 0.0005.