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. 2014 Aug 26;42(16):10720–10730. doi: 10.1093/nar/gku778

Figure 3.

Figure 3.

AUF1 promotes FST mRNA decay. (A, B) HeLa cells were transfected with siRNA targeting AUF1 together with or without plasmids expressing AUF1 isoforms. The protein level (A) and mRNA level (B) of FST were detected. (C) FST mRNA half-life was detected in cells transfected with siRNA targeting AUF1 together with or without plasmids expressing AUF1 isoforms mixture. (D) HeLa cells were transfected with siRNA targeting AUF1 together with or without plasmids expressing AUF1 isoforms. FST mRNA levels were detected at indicated times following actinomycin D treatment. Data shown are mean ± SD of three independent experiments.