Table 4.
Wound healing response pathways uniquely identified by MIPA
| Path | # Annotation genes | # Driver genes | # Sig.diff.genes | Min rank SNR | Mean rank SNR | Median rank of genes | Max rank SNR |
|---|---|---|---|---|---|---|---|
| Pentose and glucuronate interconversions [Path:mmu00040] | 27 | 17 | 1 | 2974 | 9833.75 | 11119 | 12969 |
| Synthesis and degradation of ketone bodies [Path:mmu00072] | 9 | 6 | 0 | 164 | 9381 | 10206.5 | 13030 |
| Ubiquinone and other terpenoid-quinone biosynthesis [Path:mmu00130] | 10 | 7 | 1 | 2863 | 9709.2 | 11022.5 | 13104 |
| Purine metabolism [Path:mmu00230] | 151 | 14 | 0 | 68 | 7549.297297 | 8185.5 | 13011 |
| Histidine metabolism [Path:mmu00340] | 28 | 11 | 3 | 7 | 8406.884615 | 10023 | 13052 |
| Phenylalanine, tyrosine and tryptophan biosynthesis [Path:mmu00400] | 7 | 6 | 0 | 2863 | 7231.8 | 6535 | 12654 |
| Cyanoamino acid metabolism [Path:mmu00460] | 4 | 2 | 0 | 920 | 9397.5 | 11898.5 | 12873 |
| N-Glycan biosynthesis [Path:mmu00510] | 47 | 5 | 1 | 368 | 8320.069767 | 9924 | 12896 |
| Glycosaminoglycan degradation [Path:mmu00531] | 18 | 9 | 1 | 1280 | 7398.176471 | 7623 | 13057 |
| Sphingolipid metabolism [Path:mmu00600] | 38 | 14 | 0 | 116 | 6852.361111 | 7554 | 12667 |
| Glycosphingolipid biosynthesis—globo series [Path:mmu00603] | 14 | 9 | 1 | 640 | 7690.928571 | 8637 | 13057 |
| Glyoxylate and dicarboxylate metabolism [Path:mmu00630] | 22 | 6 | 0 | 4254 | 10423.14286 | 11506 | 13065 |
| Butanoate metabolism [Path:mmu00650] | 27 | 5 | 0 | 164 | 9840.72 | 11173 | 13095 |
| One carbon pool by folate [Path:mmu00670] | 16 | 9 | 2 | 1344 | 7574.25 | 7336 | 13100 |
| Riboflavin metabolism [Path:mmu00740] | 12 | 8 | 0 | 3563 | 8754.333333 | 8901.5 | 12512 |
| Retinol metabolism [Path:mmu00830] | 63 | 38 | 4 | 38 | 7639.296296 | 7795 | 12975 |
| NF-kappa B signaling pathway [Path:mmu04064] | 84 | 13 | 0 | 14 | 4212.3125 | 2738 | 12849 |
| Phagosome [Path:mmu04145] | 150 | 26 | 1 | 46 | 4590.588785 | 3630 | 13107 |
| NOD-like receptor signaling pathway [Path:mmu04621] | 47 | 8 | 0 | 14 | 5028.02381 | 3771 | 13145 |
| RIG-I-like receptor signaling pathway [Path:mmu04622] | 59 | 11 | 1 | 24 | 4681.5 | 3239 | 12736 |
| T cell receptor signaling pathway [Path:mmu04660] | 106 | 27 | 1 | 97 | 4902.640777 | 3850 | 12928 |
| Adipocytokine signaling pathway [Path:mmu04920] | 66 | 16 | 2 | 87 | 5438.153846 | 5423 | 12745 |
| Salivary secretion [Path:mmu04970] | 70 | 28 | 1 | 589 | 5852.044776 | 5043 | 12497 |
| Bile secretion [Path:mmu04976] | 65 | 29 | 2 | 271 | 6512.473684 | 6275 | 13131 |
| Vitamin digestion and absorption [Path:mmu04977] | 21 | 14 | 1 | 634 | 6075.142857 | 6180 | 12390 |