Table 1.
Distribution volume calculated from compartmental modeling, Logan plot, MA1, and SA using regions or individual voxels
| Region |
V
T
(mL/cm
3
) |
|||||
|---|---|---|---|---|---|---|
|
Region |
Voxel |
|||||
| Unconstrained two-tissue compartment model | Logan | MA1 | SA | Logan | SA | |
| Frontal cortex |
13.3 ± 0.84 (2.7) |
12.5 ± 0.79 |
11.8 ± 0.71 |
13.6 ± 1.21 |
8.66 ± 2.14 |
13.7 ± 0.90 |
| Temporal cortex |
15.1 ± 1.04 (2.6) |
14.1 ± 0.90 |
13.5 ± 0.83 |
15.3 ± 0.85 |
9.69 ± 2.64 |
15.4 ± 0.97 |
| Hippocampus |
16.2 ± 1.11 (6.9) |
14.8 ± 1.09 |
13.8 ± 0.75 |
15.2 ± 1.74 |
6.36 ± 1.87 |
14.4 ± 1.79 |
| Parietal cortex |
13.0 ± 0.61 (2.8) |
12.3 ± 0.53 |
11.6 ± 0.40 |
13.3 ± 0.94 |
8.59 ± 2.20 |
13.5 ± 1.10 |
| Occipital cortex |
15.4 ± 1.08 (2.8) |
14.4 ± 0.99 |
13.6 ± 0.83 |
15.5 ± 1.20 |
9.87 ± 2.19 |
15.7 ± 1.13 |
| Anterior cingulum |
16.2 ± 1.56 (4.6) |
15.2 ± 1.43 |
14.7 ± 1.20 |
16.9 ± 2.02 |
9.94 ± 2.56 |
16.2 ± 0.90 |
| Caudate |
12.5 ± 1.20 (7.7) |
11.4 ± 1.00 |
11.0 ± 0.73 |
12.4 ± 1.21 |
7.17 ± 1.94 |
13.0 ± 1.36 |
| Putamen |
14.8 ± 0.67 (3.8) |
13.9 ± 0.77 |
13.3 ± 0.70 |
15.2 ± 0.80 |
10.3 ± 3.00 |
16.5 ± 0.99 |
| Thalamus |
19.3 ± 1.43 (5.6) |
17.7 ± 1.69 |
16.5 ± 1.18 |
19.5 ± 2.33 |
10.1 ± 3.11 |
19.0 ± 2.32 |
| Cerebellum | 6.73 ± 0.91 (2.5) | 6.42 ± 0.82 | 6.18 ± 0.75 | 6.83 ± 0.95 | 5.19 ± 1.98 | 7.58 ± 0.86 |
Values are presented as mean ± SD from seven human subjects. For each brain region, standard errors are listed in parentheses and are expressed as the percentage of the variable itself.