Table 1.
Characteristics peanut sensitized patients that underwent a DBPCFC
No | Sex |
Age |
Peanut-specific-IgE at diagnosis | SPT at diagnosis | Asthma # | Atopic Dermatitis $ | Clinical response to DBPCFC | GI | Resp | Syst |
---|---|---|---|---|---|---|---|---|---|---|
(years) | ||||||||||
1 |
M |
10 |
4.0 |
<1 |
- |
+ |
- |
|
|
|
2 |
M |
15 |
0.43 |
<1 |
+ |
+ |
- |
|
|
|
3 |
M |
16 |
<0.35 |
3 |
- |
- |
- |
|
|
|
4 |
M |
14 |
2.0 |
2 |
- |
- |
- |
|
|
|
5 |
M |
4 |
5.9 |
NP |
- |
- |
- |
|
|
|
6 |
F |
3 |
0.6 |
3 |
- |
+ |
- |
|
|
|
7 |
M |
13 |
1.1 |
2 |
- |
+ |
- |
|
|
|
8 |
M |
4 |
7.3 |
<1 |
+ |
+ |
- |
|
|
|
9 |
M |
15 |
0.6 |
2 |
- |
+ |
- |
|
|
|
10 |
M |
4 |
97.0 |
4 |
+ |
+ |
- |
|
|
|
11 |
M |
8 |
0.8 |
3 |
- |
- |
- |
|
|
|
12 |
F |
4 |
1.1 |
2 |
+ |
+ |
- |
|
|
|
13 |
M |
5 |
>100 |
4.5 |
- |
+ |
+ |
+ |
+ |
+ |
14 |
M |
9 |
2.2 |
1 |
+ |
- |
+ |
* |
* |
* |
15* |
F |
6 |
>100 |
3 |
- |
- |
+ |
+ |
+ |
+ |
16* |
M |
17 |
56.0 |
3.5 |
- |
+ |
+ |
- |
+ |
- |
17 |
M |
6 |
>100 |
4 |
+ |
- |
+ |
+ |
- |
- |
18 |
F |
7 |
1.9 |
4 |
+ |
+ |
+ |
+ |
+ |
- |
19 |
M |
4 |
3.5 |
NP |
- |
+ |
+ |
+ |
+ |
+ |
20 |
M |
9 |
>100 |
3 |
+ |
- |
+ |
+ |
+ |
+ |
21 |
M |
7 |
55.0 |
3 |
+ |
+ |
+ |
+ |
- |
- |
22 |
F |
7 |
2.1 |
4 |
+ |
+ |
+ |
+ |
+ |
+ |
23* |
M |
11 |
4.0 |
2 |
- |
+ |
+ |
+ |
- |
+ |
24 |
M |
4 |
6.0 |
2 |
- |
+ |
+ |
+ |
+ |
- |
25* |
F |
6 |
4.9 |
2 |
- |
+ |
+ |
+ |
+ |
+ |
26 |
M |
7 |
15.5 |
3 |
- |
- |
+ |
+ |
- |
+ |
27* |
M |
5 |
21.0 |
2 |
+ |
- |
+ |
+ |
+ |
- |
28 |
F |
6 |
5.3 |
3 |
+ |
+ |
+ |
+ |
- |
- |
29* |
M |
6 |
2.2 |
NP |
+ |
+ |
+ |
+ |
+ |
+ |
30 | F | 5 | NP | 2 | - | + | + | - | + | - |
Patient no. 1–12: non-responders to peanut challenge. Patient no. 13–30: positive responders to peanut challenge. # Asthma diagnosed according to ATS criteria.
$Atopic dermatitis diagnosed according to criteria from Hanifin and Rajka. SPT, Skin Prick Test (the number represents the wheal size ratio peanut compared to histamine). DBPCFC, Double-Blind Placebo-Controlled Food Challenge. NP, Not performed. *Children with elevated plasma IL-25 as determined in Figure 1.
GI: Gastrointestinal symptoms including stomach ache, nausea, vomiting and diarrhea; Resp: respiratory symptoms including rhinorrhea, stuffy nose; Syst: systemic symptoms including shortage of breath, systemic urticaria and angioedema.