Figure 7.
Absorbance (A490) is plotted against dilution of pools of primate plasma from 1:50 to 1:10,000 in PBS for monkeys administered the HIRMAb-IDS fusion protein at weekly doses of 3 mg/kg (panel A), 10 mg/kg (panel B), and 30 mg/kg (panel C). The pool was produced from the week 24 blood samples. The capture reagent in the sandwich ELISA is the HIRMAb-IDS fusion protein (open circles), the HIRMAb alone (closed squares), or the human IgG1κ isotype control (closed triangles). Data are mean ± SD (N=3 replicates).