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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Bioorg Med Chem Lett. 2014 Aug 28;24(19):4650–4653. doi: 10.1016/j.bmcl.2014.08.040

Figure 4.

Figure 4

(A) Binding of compound 11 to Akt1 (pdb 1O6K) as determined by GLIDE XP docking. (B) Overlay of docked conformation of 11 (green) with the bound X-ray conformation of a substrate peptide (orange). Key interactions of 11 with Akt1 are shown.