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. 2014 Sep 9;15(1):774. doi: 10.1186/1471-2164-15-774

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© Eshel et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Experimental workflow for detection of genes and miRNAs affecting SD and sex differentiation. The differentially expressed genes and miRNAs between genders and their integrative role in SD and sex differentiation are displayed. The gene expression analysis is presented on the left axis, and the miRNAs analysis on the right. The implicated conclusions integrating the two streams of data are presented in the middle. SD: Sex determination, mir: miRNA precursor, miR: expressed 3p/5p mature sequence from miRNA precursors, amh: Anti-Müllerian hormone, cr/20β-hsd: carbonyl reductase 20 beta-hydroxysteroid dehydrogenase, TGF-β: transforming growth factor beta, FDR: false discovery rate, CNV: copy number variation. Experimental flow; Implicated from the results; Implicated from the literature; Negative regulation.

Inline graphic — Experimental workflow for detection of genes and miRNAs affecting SD and sex differentiation. The differentially expressed genes and miRNAs between genders and their integrative role in SD and sex differentiation are displayed. The gene expression analysis is presented on the left axis, and the miRNAs analysis on the right. The implicated conclusions integrating the two streams of data are presented in the middle. SD: Sex determination, mir: miRNA precursor, miR: expressed 3p/5p mature sequence from miRNA precursors, amh: Anti-Müllerian hormone, cr/20β-hsd: carbonyl reductase 20 beta-hydroxysteroid dehydrogenase, TGF-β: transforming growth factor beta, FDR: false discovery rate, CNV: copy number variation. Experimental flow; Implicated from the results; Implicated from the literature; Negative regulation.