Table 4.
Differential expression between genders of miRNA and their gene targets
| Gene | miRNA1 | Overexpressed in2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | ||||||||||
| Probe3 | Gene symbol4 | Down-regulated in | miR-218 | oni-miR-E218 | oni-miR-E224 | miR-21 | pma-miR-4585 | oni-miR-E622 | bmo-miR-2779 | oni-miR-E255 | oni-miR-E304 |
| 42507 | fcgrt | Female | − | − | − | ||||||
| 86 | amh | − | − | − | + | ||||||
| 41041 | urgcp | − | − | − | − | ||||||
| 38100 | ctnnd2b | − | − | − | |||||||
| 25051 | g3s1a18 | ||||||||||
| 25051 | g3s7a7 | − | |||||||||
| 21001 | prkcb | ||||||||||
| 41366 | zbed3 | − | + | ||||||||
| 41366 | 7813 | − | − | ||||||||
| 41366 | 5031 | − | − | ||||||||
| 41052 | urgcp | − | − | − | − | + | |||||
| 21060 | cyp4f3 | − | − | − | − | ||||||
| 14085 | wasp1 | − | |||||||||
| 22935 | urgcp | − | − | − | + | ||||||
| 27670 | zebd3 | − | + | ||||||||
| 25225 | cdh1 | ||||||||||
| 39928 | gpr144 | − | − | − | + | + | |||||
| 16862 | ror1 | − | − | ||||||||
| 28545 | fam131c | Male | + | − | |||||||
| 10109 | eci1 | + | + | ||||||||
| 5193 | itgb3a | + | |||||||||
| 13137 | timm50 | + | + | + | + | ||||||
| 555 | fndc7 | + | + | ||||||||
| 35393 | nkain1 | + | |||||||||
| 6825 | kiaa1468 | + | |||||||||
| 7935 | rasgef1b | + | + | + | |||||||
| 452 | higd1a | + | + | + | |||||||
| 5723 | sult3 | + | |||||||||
| 30073 | casp8 | + | − | ||||||||
| 23873 | orni-dba | + | |||||||||
| 20878 | hspa5 | + | |||||||||
| 31928 | socs7 | + | |||||||||
| 9238 | atp5g3 | + | + | ||||||||
| 3491 | LOC100703324 | + | + | ||||||||
| 35899 | LOC100707490 | + | + | ||||||||
| 800 | mrpl34 | + | + | ||||||||
| 23235 | psmb8 | + | |||||||||
| 13679 | ankrd22 | + | + | − | |||||||
| 24221 | LOC100690239 | + | |||||||||
| 5738 | sult3st1 | + | |||||||||
| 25471 | rtn4ip1 | + | |||||||||
| 1524 | zp3 | + | |||||||||
| 9317 | gpa33 | + | + | ||||||||
| 1135 | cr/20β-hsd | + | + | ||||||||
| Rate of concordant target sites | 6/15 | 2/5 | 7/17 | 8/15 | 6/6* | 13/21 | 2/2 | 2/4 | 3/4 | ||
Concordant and discordant differential expression is displayed for nine miRNAs with their forty four differentially expressed between genders predicted gene targets by a false discovery rate of p < 0.05.
1miR: expressed 3p/5p mature sequence from miRNA precursors.
2Target recognition sites for miRNAs are represented by concordant (+) or discordant (−) differential expression, respectively, assuming that up-regulated miRNAs down-regulate their target sites [74].
3Probe numbers begin with the prefix “CUST_”.
4Gene symbol based on NCBI, ENSEMBL or tilapia LOC no. urgcp and zbed3 genes represent different probes at multiple locations in the genome.
*The probability that the rate of concordant target sites should occur by chance is: (1/2)6 = 0.015.