Table 1.
Genes differentially expressed in the zur mutant
| Gene number | Gene name | Predicted Zur binding sequence | Predicted functiona | Fold change (zur/wt) |
|---|---|---|---|---|
| Upregulated | ||||
| CC0214 | znuL | TACGTTATTTCATAACAGT | TonB-dependent receptor | 5.02 |
| CC0320 | zrpW | AATGTTACTTTATAACACG | Hypothetical protein (putative transporter domain) | 8.15 |
| CC0482 | 5-methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase (EC:2.1.1.14) | 2.33 | ||
| CC0663b | znuM | CCTGTTACAGAATAACAGG | TonB-dependent receptor | 7.21 |
| CC1517 | znuK | GATGTTATATCATAACAAT | TonB-dependent receptor | 41.30 |
| CC1518 | znuG | ATTGTTATGATATAACATC | ABC-2 type transport system ATP-binding protein | 29.39 |
| CC1519 | znuH | ABC-2 type transport system permease protein | 38.09 | |
| CC1520 | znuI | ABC-2 type transport system permease protein | 11.61 | |
| Downregulated | ||||
| CC0027 | PKHD-type hydroxylase (2OG-Fe(II) oxygenase superfamily) | 0.31 | ||
| CC0711 | feoA | Ferrous iron transport protein A | 0.45 | |
| CC1775 | Hypothetical protein (DUF2946 domain) | 0.37 | ||
| CC1776 | Transcriptional regulator (GntR family) | 0.48 | ||
| CC1777 | sodA | Superoxide dismutase, Fe-Mn family | 0.23 | |
| CC1778 | TonB-dependent receptor | 0.44 | ||
| CC1780 | ThiJ/PfpI protease family protein | 0.50 | ||
| CC1782 | Hypothetical protein | 0.47 | ||
| CC2192 | Hypothetical protein (DUF3297 and Maf-like domains) | 0.44 | ||
| CC2193 | Hypothetical protein | 0.48 | ||
| CC2720b | GCCGTAATTAAGTAACAGA | Hypothetical protein (Predicted periplasmic or external membrane component protein with DUF2946 domain) | 0.46 | |
| CC2721 | czrC | RND system | 0.29 | |
| CC2722b | czrB | RND system | 0.59 | |
| CC2723 | Hypothetical protein (Predicted periplasmic protein) | 0.46 | ||
| CC2724 | czrA | RND system | 0.40 | |
| CC2725 | Hypothetical protein (Predicted cytoplasmic membrane component with DUF190 domain) | 0.38 | ||
| CC2726 | zntA | P-type ATPase | 0.31 | |
| CC2727 | Hypothetical protein (glutaredoxin domain) | 0.40 | ||
| CC2927 | Hypothetical protein (PepSY-associated TM helix) | 0.41 | ||
| CC2928 | TonB-dependent receptor | 0.46 | ||
| CC3060 | Hypothetical protein (Predicted periplasmic protein with DUF2271 domain) | 0.50 | ||
| CC3061 | Hypothetical protein (DUF4198 domain) | 0.41 | ||
| CC3263 | bfd | Hypothetical protein (Fer2_BFD domain) | 0.28 | |
aProtein function is described as annotated at the KEGG website.
bThese genes had altered expression in the zur mutant but did not reach the cutoff criteria established for differentially expressed genes.