Table 2.
Demographics and baseline characteristics of the enrolled sample.
| Total sample |
Placebo | Ghrelin 1 mcg/Kg |
Ghrelin 3 mcg/Kg |
P value |
|
|---|---|---|---|---|---|
| Number (n) | 45 | 18 | 13 | 14 | |
| Females(%) | 36 | 39 | 31 | 36 | .90 |
| Age (years) | |||||
| range | 25–62 | 28–62 | 25–57 | 25–58 | |
| M ± SD | 44.7 ± 9.1 | 46.6 ± 9.0 | 42.8 ± 9.8 | 43.9 ± 8.6 | .49 |
| median | 47 | 48 | 43 | 45 | |
| Race/Ethnicity (%) | |||||
| Black | 31.1 | 22.2 | 38.5 | 35.7 | |
| White | 53.3 | 61.1 | 46.2 | 50.0 | |
| Latino | 4.4 | 5.6 | 7.7 | 0 | |
| Others | 11.1 | 11.1 | 7.7 | 14.3 | |
| BMI [M ± SD] | 25.8 ± 3.1 | 26.4 ± 2.5 | 25.2 ± 3.3 | 25.7 ± 3.7 | .56 |
| Age of onset for alcohol problems | |||||
| range | 12–52 | 12–52 | 14–33 | 15–36 | |
| M ± SD | 21.8 ± 8.1 | 22.9 ± 10.9 | 20.3 ± 5.2 | 21.8 ± 6.0 | .68 |
| median | 20 | 20 | 19 | 20 | |
| 90-day baseline drinks/drinking day | 11.8 ± 6.8 | 11.8 ± 7.9 | 11.8 ± 6.8 | 11.8 ± 5.7 | 1.00 |
| Number of drinks the day before the experimental session | 4.5 ± 5.5 | 4.2 ± 5.3 | 4.9 ± 5.7 | 4.5 ± 5.8 | .94 |
| Alcohol Dependence Severity (ADS) | 11.4 ± 7.0 | 12.6 ± 8.4 | 9.0 ± 4.4 | 12.0 ± 6.8 | .35 |
| CIWA-Ar | 1.2 ± 1.6 | 1.7 ± 2.0 | 1.1 ± 1.4 | 0.6 ± 0.8 | .15 |
| 90-day baseline cigarettes/day* | 14.8 ± 10.5 | 16.6 ± 10.8 | 16.4 ± 14.1 | 11.1 ± 5.1 | .42 |
M: Median; SD: Standard Deviation; BMI: Body Mass Index; drink = Standard Drinking Unit (SDU); CIWA-Ar: Clinical Institute Withdrawal Assessment of Alcohol Scale, Revised
*
76% of the sample were smokers.