Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalized onset tonic-clonic seizures

. Author manuscript; available in PMC: 2014 Sep 27.

Published in final edited form as: Cochrane Database Syst Rev. 2003 Apr 22;(2):CD002217. doi: 10.1002/14651858.CD002217

Methods	Random list generated using computer generated random numbers. Concealment by placebo dummies. Double blind.
Participants	People with previously untreated epilepsy. Number randomized = PHB group = 51 people, PHT group = 52 people. None of the participants had partial epilepsy. 54% of the participants were male. Age range: 4-12 years. Range of follow-up (months), 22-36.
Interventions	Monotherapy with PHB or PHT. Dose achieved not stated.
Outcomes	Proportion with recurrence of seizures. Adverse effects.
Notes
*Risk of bias*
Item	Authors’ judgement	Description
Allocation concealment?	Yes	A - Adequate

IPD: individual patient data

PHT: phenytoin