Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalized onset tonic-clonic seizures

. Author manuscript; available in PMC: 2014 Sep 27.

Published in final edited form as: Cochrane Database Syst Rev. 2003 Apr 22;(2):CD002217. doi: 10.1002/14651858.CD002217

Methods	A crossover trial with 21 day treatment periods. Double blind. Randomization method not stated. Method of allocation concealment not stated.
Participants	Institutionalized adult patients with uncontrolled epilepsy. 91% of participants had partial epilepsy. Number randomized = PHB group = 45 people, PHT group = 45 people. 62% of participants were male. Age range 18-51 years.
Interventions	Monotherapy with PHB or PHT. Median daily dose achieved not stated.
Outcomes	Seizure frequency. Time to treatment withdrawal.
Notes
*Risk of bias*
Item	Authors’ judgement	Description
Allocation concealment?	Unclear	B - Unclear