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. 2014 Sep 24;9(9):e107830. doi: 10.1371/journal.pone.0107830

Figure 2. Inhibition of gastric tumor growth by pseudolaric acid B and mean body weight change of nude mice.

Figure 2

A: growth curve of SGC7901 cell xenografts B: growth curve of SGC7901/ADR cell xenografts C: relative body weight change of mice with SGC7901 cell xenografts D: relative body weight change of mice with SGC7901/ADR cell xenografts. SGC7901 cells and SGC7901/ADR cells (2.5×106/ml) were injected subcutaneously into the axillary areas of nude mice, and when evident tumors were observed, the mice received a daily dose of 25 mg/kg pseudolaric acid B and/or 1.25 mg/kg adriamycin or normal saline (control)/tween solution (control) (n = 5 per group). Tumor volumes were monitored at different time points (Day1, 3, 5, 7, 9, 11, 13, 15, 17, 19). The IR of tumor growth in the drug-treated groups were compared with that in the control groups at the end of the experiment by one-way ANOVA. *p<0.05 vs control group.