Table 2. Average optical density of Cox-2, PKC-α and P-gp in different treatment groups (mean ± SD).
Group | n | Cox-2 | PKC-α | P-gp |
NS control group (SGC7901) | 5 | 0.243±0.011* | 0.192±0.012* | 0.219±0.008* |
NS control group (SGC7901/ADR) | 5 | 0.302±0.004 | 0.285±0.006 | 0.292±0.008 |
TWEEN control group (SGC7901/ADR) | 5 | 0.304±0.007 | 0.287±0.007 | 0.291±0.010 |
ADR group (SGC7901/ADR) | 5 | 0.291±0.007* | 0.252±0.002* | 0.261±0.005* |
PAB group (SGC7901/ADR) | 5 | 0.255±0.004* | 0.222±0.002* | 0.241±0.005* |
PAB+ADR group (SGC7901/ADR) | 5 | 0.236±0.002* | 0.183±0.009* | 0.226±0.003* |
Notes: * p<0.05 vs control group.
n: number of animals.
PAB, Pseudolaric acid B; ADR, adriamycin; SD, standard deviation.