Table 1.
Characteristics of the 185 patients with Non Specific Pattern of Lung Function
| Characteristic | 185 patients with NSP |
|---|---|
| Mean ± SD (except when stated) or n | |
| Sex, Female/Male | 99/86 |
| Age, years | 57 ± 19 |
| BMI, kg.m−2 | 26.9 ± 8.4 |
| BMI ≥ 30/25 to 30/< 25 kg.m−2 | 49/55/81 |
| Smoking history | |
| Never smokers, n | 105 |
| Ex-smokers, n | 48 |
| Current smokers, n | 32 |
| Pack-year, median [interquartile] | 0 [0 ; 35] |
| MRC score, median [interquartile] | 2.0 [1.0 ; 2.0] |
| FEV1, L | 1.96 ± 0.68 |
| FEV1,% predicted [12] | 66 ± 9 |
| FEV1, z-score | - 2.51 ± 0.61 |
| FVC, L | 2.66 ± 0.82 |
| FVC,% predicted [12] | 67 ± 9 |
| FVC, z-score | - 2.58 ± 0.71 |
| FEV1/FVC | 0.77 ± 0.08 |
| FEV1/FVC,% predicted [12] | 99 ± 9 |
| FEV1/FVC, z-score | - 0.24 ± 0.98 |
| Slow inspiratory VC, L | 2.71 ± 0.79 |
| Slow inspiratory VC,% predicted [13] | 76 ± 11 |
| FEV1 / Slow inspiratory VC | 0.75 ± 0.08 |
| FEV1 / Slow inspiratory VC, 5th percentile [13] | 0.68 ± 0.04 |
| TLC, L | 5.49 ± 1.19 |
| TLC,% predicted [14] | 96 ± 12 |
| TLC, 5th percentile | 4.66 ± 1.07 |
| FRC, L | 3.46 ± 0.92 |
| FRC,% predicted [14] | 111 ± 27 |
| RV, L | 2.68 ± 0.85 |
| RV,% predicted [14] | 131 ± 33 |
| Rawtot, kPa.s.L−1 | 0.46 ± 0.28 |
| Rawtot,% predicted | 154 ± 99 |
| Specific Rawtot, kPa.s | 1.60 ± 0.98 |
| Specific Rawtot,% predicted | 166 ± 101 |
| VA, L (n patients with measurement)* | 4.01 ± 0.90 (62) |
| VA/TLC (n patients with measurement) | 0.75 ± 0.12 (62) |
Set of predicted values are quoted in the first column.
*: among these 62 patients, 53 (85%) depicted a restrictive defect defined by VA below the 5th percentile value of TLC minus 150 mL.