Table 6.
Study | Year | Population (n) |
Follow up (Years) |
Comparison Groups |
Histology Classification |
All-Cause Mortality |
Liver- Related Mortality |
Cardiovascular Mortality |
Cancer related Mortality |
---|---|---|---|---|---|---|---|---|---|
Matteoni [15] | 1999 | 132 | 18 | NASH versus steatosis± inflammation | Matteoni | 39.7% versus 32.2%● | 10.9% versus 1.69%* | NR | NR |
Ekstedt [14] | 2006 | 129 | 13.7 | NASH versus steatosis± non-specific inflammation | Brunt | 26.7% versus 12%● | 2.8% versus none● | 15.5% versus 8.6%● | 5.6% versus 1.7%● |
Rafiq [16] | 2009 | 173 | 18.5 | NASH versus steatosis± non -specific inflammation | Matteoni | No differences between both groups (P=0.30) | 17.5% versus 2.5% † | NR | NR |
Soderberg [46] | 2010 | 118 | 45 | NASH versus simple steatosis | Kleiner | 47 % versus 34.3 %● | 5.8% versus 8.9%● | 13.7% versus 10.4%● | 15.6% versus 7.4%● |
Younossi[17] | 2011 | 209 | 12 | NASH versus No NASH | Younossi | 30.5% versus 30.8%* | 13% versus 1.3% † | NR | NR |
NR-Not Reported,
- P<0.05,
-Significance not reported,
-Not significant