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. Author manuscript; available in PMC: 2014 Sep 27.
Published in final edited form as: Clin Liver Dis. 2012 Jun 27;16(3):487–504. doi: 10.1016/j.cld.2012.05.006

Table 6.

Studies comparing the overall and cause-specific mortality in no NASH compared to NASH

Study Year Population
(n)
Follow
up
(Years)
Comparison
Groups
Histology
Classification
All-Cause
Mortality
Liver-
Related
Mortality
Cardiovascular
Mortality
Cancer
related
Mortality
Matteoni [15] 1999 132 18 NASH versus steatosis± inflammation Matteoni 39.7% versus 32.2% 10.9% versus 1.69%* NR NR
Ekstedt [14] 2006 129 13.7 NASH versus steatosis± non-specific inflammation Brunt 26.7% versus 12% 2.8% versus none 15.5% versus 8.6% 5.6% versus 1.7%
Rafiq [16] 2009 173 18.5 NASH versus steatosis± non -specific inflammation Matteoni No differences between both groups (P=0.30) 17.5% versus 2.5% NR NR
Soderberg [46] 2010 118 45 NASH versus simple steatosis Kleiner 47 % versus 34.3 % 5.8% versus 8.9% 13.7% versus 10.4% 15.6% versus 7.4%
Younossi[17] 2011 209 12 NASH versus No NASH Younossi 30.5% versus 30.8%* 13% versus 1.3% NR NR

NR-Not Reported,

- P<0.05,

-Significance not reported,

*

-Not significant