Table 2.
Reduction in Zic3 expression results in an array of heart defects
| E9-9.5 Number of embryos (n) |
13 | 4 | 2 | 1 | 1 | % of Total n=21 |
|---|---|---|---|---|---|---|
| Normal | + | 62% | ||||
| Simple tube | + | + | 24% | |||
| L-looped | + | 10% | ||||
| Partially looped | + | 5% | ||||
| Situs abnormality | + | 5% |
| E10.5–11.5 Number of embryos (n) |
28 | 5 | 3 | 3 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | % of Total n=49 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Normal | + | 57% | ||||||||||
| Inferior/superior ventricles | + | + | + | 16% | ||||||||
| Single ventricle | + | + | + | + | 18% | |||||||
| Simple tube | + | + | 10% | |||||||||
| L-looped | + | + | + | + | + | 14% | ||||||
| Situs abnormality | + | + | + | + | 8% | |||||||
| Pericardial edema | + | + | 10% |
| E12.5–14.5 Number of embryos (n) |
15 | 1 | 1 | 1 | 1 | 1 | 1 | % of Total n=49 |
|---|---|---|---|---|---|---|---|---|
| Normal | + | 71% | ||||||
| Interior/superior ventricles | + | + | 10% | |||||
| Single ventricle | + | 5% | ||||||
| Single atrium | + | + | 10% | |||||
| L-looped | + | + | 10% | |||||
| Pericardial edema | + | + | 10% |