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. Author manuscript; available in PMC: 2014 Sep 27.
Published in final edited form as: Cell Rep. 2014 May 10;7(4):1065–1076. doi: 10.1016/j.celrep.2014.03.076

Figure 2. KL-VS-associated cognitive enhancement is independent of age.

Figure 2

(A–C) Global composite Z-scores decreased as a function of age in non-carriers (empty squares) and carriers (purple squares) of the KL-VS allele in (A) Cohort 1, (B) Cohort 2, and (C) Cohort 3. (D) In meta-analysis of all cohorts, KL-VS-associated cognitive enhancement tended to decrease with advancing age (ANOVA, KL-VS:age interaction, p=0.10). Data were analyzed by linear models, accounting for effects of age, sex, and education and testing for effects due to an age by KL-VS interaction. APOEε4 carrier status had no significant effects on these measures. See also Tables S5 and S6. Data are means ± SEM.

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