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. Author manuscript; available in PMC: 2014 Sep 27.
Published in final edited form as: Cell Rep. 2014 May 10;7(4):1065–1076. doi: 10.1016/j.celrep.2014.03.076

Figure 4. Klotho elevation also improves working and context memory without altering other behaviors in young mice.

Figure 4

(A) Percent alternations among arms by 3–4-month-old mice during exploration of a Y-maze (n=8–10 mice per genotype). (B) Percent time 6-month-old mice spent freezing at baseline and 24 h after context training in a fear conditioning task (n=6–7 male mice per genotype). (C) Movements during exploration of an open field (n=13–14 mice per genotype; p=0.30 by two-tailed t-test). (D) Percent time spent exploring the open arms of an elevated plus maze (n=14–15 mice per genotype; p=0.60 by two-tailed t-test). *p<0.05, ***p<0.001 vs chance or as indicated by bracket (t-test). See also Figure S3. Data are means ± SEM.