Table 3.
Genotype frequencies for PTPN22 rs2476601 and genotype effects of studies included in the meta-analysis
| Author | Total number | Case genotype | Control genotype | T allele prevalence | T versus C | TT versus CC | CT versus CC | HWE | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Control | TT | CT | CC | TT | CT | CC | OR | 95 % CI | OR | 95 % CI | OR | 95 % CI | ||||||
| Kalle Kisand | 65 | 229 | 1 | 15 | 49 | 6 | 51 | 172 | 0.138 | 0.943 | 0.531 | 1.676 | 0.585 | 0.069 | 4.976 | 1.032 | 0.535 | 1.992 | P = 0.40 |
| Anna Okruszko | 80 | 151 | 9 | 20 | 51 | 1 | 36 | 114 | 0.126 | 2.164 | 1.315 | 3.561 | 20.118 | 2.483 | 163.008 | 1.242 | 0.656 | 2.352 | P = 0.47 |
| Camilla Cervin | 341 | 1,453 | 7 | 92 | 242 | 18 | 257 | 1,178 | 0.101 | 1.641 | 1.291 | 2.086 | 1.893 | 0.782 | 4.582 | 1.743 | 1.323 | 2.295 | P = 0.38 |
| Antonio Petrone | 250 | 545 | 1 | 31 | 218 | 2 | 47 | 496 | 0.047 | 1.440 | 0.917 | 2.261 | 1.138 | 0.103 | 12.612 | 1.501 | 0.928 | 2.427 | P = 0.33 |
| Elin Pettersen | 123 | 1,491 | 1 | 32 | 90 | 18 | 292 | 1,181 | 0.110 | 1.298 | 0.888 | 1.897 | 0.729 | 0.096 | 5.523 | 1.438 | 0.942 | 2.196 | P = 0.99 |
| Overall odds ratio | 1.518 | 1.286 | 1.792 | 1.861 | 0.940 | 3.684 | 1.523 | 1.260 | 1.840 | ||||||||||
HWE Hardy–Weinberg equilibrium