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Cells were incubated in 96-well plates coated with laminin (LN) or fibronectin (FN) respectively for 48 hours. The MTT assays showed that the lower-level expression of integrin α6 caused decreased proliferation of HCC cells with significant statistical difference (P < 0.05) in the cells incubated on LN, while the cells incubated on FN did not show any statistically significant effect (P > 0.05). *P < 0.05, ****P < 0.0001 compared with control group.
