Table 3.
Association of SNX24 genetic variants with CAA formation risk in Taiwanese Kawasaki disease by logistic regression analysis
| SNX24 genetic variants | Odds ratio | 95% CI | p value |
|---|---|---|---|
|
Adjusted by fever duration (days) |
|
|
|
| rs154507 |
1.90 |
0.88-2.83 |
0.046 |
| rs27740 |
1.90 |
0.88-2.83 |
0.046 |
| rs26371 |
0.60 |
0.32-1.04 |
0.105 |
| rs6595415 |
1.74 |
0.84-2.64 |
0.077 |
| rs17149732 |
1.74 |
0.84-2.64 |
0.077 |
| rs17149748 |
1.83 |
0.86-2.72 |
0.057 |
| rs1038078 |
1.71 |
0.82-2.58 |
0.087 |
| rs28891 |
0.41 |
0.25-0.75 |
0.003
|
| rs6595423 |
1.74 |
0.84-2.64 |
0.077 |
|
Adjusted by 1st IVIG used (days after the first date with fever) |
|
|
|
| rs154507 |
1.61 |
0.88-2.83 |
0.114 |
| rs27740 |
1.61 |
0.88-2.83 |
0.114 |
| rs26371 |
0.57 |
0.32-1.04 |
0.059 |
| rs6595415 |
1.52 |
0.84-2.64 |
0.152 |
| rs17149732 |
1.52 |
0.84-2.64 |
0.152 |
| rs17149748 |
1.57 |
0.86-2.72 |
0.127 |
| rs1038078 |
1.50 |
0.82-2.58 |
0.171 |
| rs28891 |
0.42 |
0.25-0.75 |
0.002
|
| rs6595423 | 1.52 | 0.84-2.64 | 0.152 |
SNX24, sorting nexin 24; IVIG, Intravenous immunoglobulin; CAA, Coronary artery aneurysm; CI, confidence interval.
A logistic regression model was performed by using the indicated predictors including fever duration (days) or 1st IVIG used time (days after the first date with fever).
Bold, emphasizing statistical significance was considered as p value <0.006 (0.05/9).