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. Author manuscript; available in PMC: 2015 Oct 28.
Published in final edited form as: Org Biomol Chem. 2014 Oct 28;12(40):8048–8060. doi: 10.1039/c4ob01079e

Table 3.

Optimization of subunit C.In vitro anti-influenza A virus activities of compounds8a-f.a

Compd. Structure EC50 (μM)
P114F5 graphic file with name nihms-625870-t0022.jpg 13.9
8a graphic file with name nihms-625870-t0023.jpg >100
8b graphic file with name nihms-625870-t0024.jpg >100
8c graphic file with name nihms-625870-t0025.jpg 79.0
8d graphic file with name nihms-625870-t0026.jpg 36.2
8e graphic file with name nihms-625870-t0027.jpg 19.5
8f graphic file with name nihms-625870-t0028.jpg 10.0
a

Using influenza virus A/Udorn/72 strain (H3N2).