Table 3.
Optimization of subunit C.In vitro anti-influenza A virus activities of compounds8a-f.a
| Compd. | Structure | EC50 (μM) |
|---|---|---|
| P114F5 |
|
13.9 |
| 8a |
|
>100 |
| 8b |
|
>100 |
| 8c |
|
79.0 |
| 8d |
|
36.2 |
| 8e |
|
19.5 |
| 8f |
|
10.0 |
Using influenza virus A/Udorn/72 strain (H3N2).