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. Author manuscript; available in PMC: 2015 Oct 28.
Published in final edited form as: Org Biomol Chem. 2014 Oct 28;12(40):8048–8060. doi: 10.1039/c4ob01079e

Table 7.

EC50 values (μM) against various influenza virus strains of compound 11e and HTS hit P114F5.a

Virus. 11e P114F5
Influenza A/udorn/72 (H3N2) 0.10 13.9
Influenza A/PR/8/34 (H1N1) 0.07 8.78
Influenza A1/Jingfang 86-1(H1N1) 0.10 9.05
Influenza A3/Lufang 93-1(H3N2) 0.06 11.7
Influenza B/Shenzhen/747 0.05 10.9
a

EC50 values are the compound concentrations for 50% reduction of plaques.