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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Biol Psychiatry. 2014 Mar 26;77(5):445–453. doi: 10.1016/j.biopsych.2014.03.020

Figure 2.

Figure 2

Effect of decreased MD activity on extinction and reversal learning task. A, Schematic drawing of the experiment design. Abbreviations: Visual stimulus 1 (S1), visual stimulus 2 (S2), lever-press response (R), outcome (milk) (O). B, Discrimination task, ratio between mean S+ and S− response rate (±SEM) (GFP-Sal n=15, hM4D-Sal n=29). C, Extinction task. mean lever press performed per minute (±SEM) during S+ and S− presentations (GFP-Sal n=8, GFP-CNO n=7, hM4D-Sal n=15, hM4D-CNO n=14). D, Reversal task, ratio between mean S+ and S− response rate (±SEM) (GFP-Sal n=8, GFP-CNO n=5, hM4D-Sal n=13, hM4D-CNO n=15).