Table 2.

Results of the Cox regression

	Significance	Hazard ratio	95% confidence interval for hazard ratio
			Lower limit	Upper limit
Hormone-receptor status positive	p < 0.001	0.599	0.475	0.755
CNS metastases	p < 0.001	2.479	1.547	3.972
Age at initial diagnosis of metastasis [years]	p < 0.001	1.015	1.007	1.022
Time [months] between initial diagnosis and metastasis	p < 0.001	0.996	0.995	0.998
Number of metastatic localizations	p = 0.010	1.182	1.041	1.342