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. 2014 Sep 15;14:337. doi: 10.1186/1472-6882-14-337

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© Khan et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Transmission electron micrograph of the 48 h grown C. albicans 04 cells in the absence and presence of sub-MICs of oils. (A) Untreated; intact cell wall, cell membranes and other organelles. (B, C) Cells grown in the presence of C. copticum at 90 μg.mL⁻¹; loosening of cell membrane (1), disorganized cytoplasm (2), deposition of lipid globules (3), excessive vacuolization (4). (D,E) Cells grown in the presence of T. vulgaris at 90 μg.mL⁻¹; disorganized protoplasm with receding of cell membrane (5), thickening of cell wall (6). (F) Cells grown in the presence of thymol at 90 μg.mL⁻¹; lysis of cell wall and shrinkage of cell (7).