Table 1.
PICU Infections by Cancer Type
| N | Sepsis (%) |
Gram(+) (%) |
Gram(−) (%) |
Fungal (%) |
Viral (%) |
||
|---|---|---|---|---|---|---|---|
| SOLID CANCERS | 5718 | 530 (9) | 176 (3) | 221 (4) | 115 (2) | 195 (3) | |
| Central Nervous System | 3502 | 167 (5) | 101 (3) | 106 (3) | 62 (2) | 93 (3) | |
| Peripheral Nervous System | 781 | 111 (14) | 31 (4) | 36 (5) | 14 (2) | 46 (6) | |
| Bone | 437 | 105 (24) | 20 (5) | 24 (5) | 12 (3) | 18 (4) | |
| Sarcoma | 331 | 65 (20) | 6 (2) | 16 (5) | 19 (6) | 9 (3) | |
| Liver | 265 | 33 (12) | 9 (3) | 26 (10) | 3 (1) | 16 (6) | |
| Kidney | 262 | 31 (12) | 6 (3) | 8 (3) | 4 (2) | 13 (5) | |
| Germ Cell Tumor | 140 | 18 (13) | 3 (2) | 5 (4) | 1 (1) | 0 (0) | |
| HEMATOLOGIC CANCERS | 4647 | 1232 (27) | 327 (7) | 322 (7) | 308 (7) | 432 (9) | |
| Acute Lymphoid Leukemia | 2611 | 655 (25) | 147 (6) | 187 (7) | 201 (8) | 266 (10) | |
| Acute Myeloid Leukemia | 902 | 316 (35) | 102 (11) | 80 (9) | 64 (7) | 81 (9) | |
| Hodgkins Lymphoma | 301 | 92 (31) | 20 (7) | 14 (5) | 5 (2) | 20 (7) | |
| Not Elsewhere Classified | 272 | 43 (16) | 19 (7) | 20 (7) | 21 (8) | 19 (7) | |
| Burkitt’s Lymphoma | 171 | 41 (24) | 17 (10) | 6 (4) | 5 (3) | 11 (6) | |
| Non-Hodgkins Lymphoma | 160 | 42 (26) | 7 (4) | 6 (4) | 5 (3) | 8 (5) | |
| Myelodysplastic Syndrome | 109 | 29 (27) | 10 (9) | 9 (8) | 6 (6) | 25 (23) | |
| Chronic Myeloid Leukemia | 62 | 12 (19) | 5 (8) | 0 (0) | 4 (6) | 1 (2) | |
| Peripheral T-Cell Lymphoma | 59 | 2 (3) | 0 (0) | 0 (0) | 1 (2) | 1 (2) | |
| RR 2.9a (2.6–3.1) p<0.001 | RR 2.3a (1.9–2.7) p<0.001 | RR 1.8a (1.5–2.1) p<0.001 | RR 3.3a (2.7–4.1) p<0.001 | RR 2.7a (2.3–3.2) p<0.001 | |||
a
relative risk with 95% CI for admissions with hematologic cancers, compared to admissions with solid cancers