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. Author manuscript; available in PMC: 2015 Oct 7.
Published in final edited form as: Vaccine. 2014 Aug 27;32(44):5824–5831. doi: 10.1016/j.vaccine.2014.08.030

Fig. 5. Mucosal antibody responses, pro-inflammatory cytokine and lung viral titers upon heterosubtypic challenge.

Fig. 5

Levels of IgG antibodies to virus or M2e antigens were determined in lung or BALF samples (N=4) at day 4 post-challenge after split or split and additional M2e5x VLP immunization. (A) Virus specific IgG antibody response. (B) M2e specific IgG antibody response. (C) Levels ofIL-6 cytokine in BALF. (D) Lung viral titers. Error bars indicate mean ± SEM. P value indicates significant difference. BALF, bronchoalveolar lavage fluid; pg, picogram.