Fig. 2. Conceptual diagram of the epigenetic effects of fetal alcohol exposure on POMC gene in the hypothalamus.
Dnmt=DNA methyltransferase, MBD (methyl-binding domain proteins), HDAC=histone deacetylase, HAT= Histone acetyltransferase, Ac=acetylation, FAE=fetal alcohol exposure, TSA=trichostatin, 5′-Aza=5′-azacytidine, CH3=methyl group, SAM=S-adenosylmethionine.