Table 3.
Aberrantly hypermethylated miRNAs in PC and PN in present and previous studies
| Names | Differently methylated region location in genome | -10log ( P )* | Transcription direction | References | |
|---|---|---|---|---|---|
|
Hypermethylated |
hsa-mir-9-3 |
chr15:89908727-89909052 |
78.11 |
Sense |
[24] |
| hsa-mir-9-1 |
chr1:156389946-156390692 |
81.02 |
Antisense |
[25] |
|
| hsa-mir-124-3 |
chr20:61806943-61807560 |
30.36 |
Sense |
[21] |
|
| hsa-mir-10b |
chr2:177013457-177013940 |
366.4 |
Sense |
[28,29] |
|
| hsa-mir-124-2 |
chr8:65289087-65292713 |
387.77 |
Sense |
[20,26] |
|
| hsa-mir-718 |
chrX:153284470-153285204 |
65.44 |
Antisense |
|
|
| hsa-mir-203 |
chr14:104584097-104584701 |
92.85 |
Sense |
[27] |
|
| Hypomethylated | hsa-mir-210 |
chr11:569133-569765 |
95.42 |
Antisense |
[23] |
| hsa-mir-1469 |
chr15:96877281-96877871 |
81.68 |
Sense |
|
|
| hsa-mir-130b |
chr22:22006547-22007358 |
143.05 |
Sense |
[22] |
|
| hsa-mir-149 |
chr2:241395079-241395714 |
58.15 |
Sense |
|
|
| hsa-mir-1224 |
chr3:183958940-183960006 |
126.15 |
Sense |
|
|
| hsa-mir-564 | chr3:44902453-44903064 | 46.02 | Sense |
*Logarithmic transformation of P to show significance level of the differential methylation region (in differently methylated region (DMR) estimation) or methylation blocks (model-based analysis of ChIP-Seq). The higher this value, the higher the probability inferred for DMR or methylation block.