Table 2.
Associations of Clinical and Radiological Characteristics
| Ground Glass Opacitya | ≥ 5 Pulmonary Nodulesa | Bronchiectasis Only | No Lung Diseaseb | |
|---|---|---|---|---|
| Number of Subjects | 18 | 34 | 9 | 13 |
| Female (%) | 20 (56) | 20 (59) | 5 (56) | 7 (54) |
| Median Age (% > 50 years) | 44 (33) | 45 (35) | 60 (67) | 43 (39) |
| Subjects (%) with: | ||||
| Ground Glass | 18(100) | 13 (38) | 0 (0) | 0 (0) |
| ≥ 1 Nodule | 16 (89) | 34 (100) | 4 (44) | 3 (23) |
| Bronchiectasis | 6 (33) | 12 (35) | 9 (100) | 0 (0) |
| Hilar Adenopathy | 11 (61) | 24 (71) | 3 (33) | 0 (0) |
| History of Pneumonia | 8 (44) | 21 (62) | 7 (78) | 7 (54) |
| Splenomegaly/Splenectomy | 10 (56) | 24 (71) | 1 (11) | 1 (8) |
| AIHA/ITP | 9 (50) | 21 (62) | 0 (0) | 1 (8) |
| Liver Disease | 5 (28) | 6 (18) | 0 (0) | 0 (0) |
| Enteropathy | 2 (11) | 3 (9) | 1 (11) | 1 (8) |
| ILD | No ILD | |||
| Number of Subjects | 39 | 22 | ||
| Subjects (%) with: | p value | |||
| History of Pneumonia | 22 (56) | 14 (64) | 0.78 | |
| Splenomegaly/Splenectomy | 24 (63) | 2 (9) | <0.0001 | |
| AIHA/ITP | 22 (56) | 1 (5) | <0.0001 | |
| Liver Disease | 8 (21) | 0 (0) | 0.042 | |
| Enteropathy | 4 (10) | 2 (9) | 1.00 | |
AIHA = autoimmune hemolytic anemia ILD = interstitial lung disease ITP = immune thrombocytopenic purpura
a
patients included in both groups if both ground glass opacity and > 5 pulmonary nodules were present
b
includes patients with no CT findings and those with 1-4 pulmonary nodules but no bronchiectasis or ground glass opacity