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. 2014 Sep 20;3:542. doi: 10.1186/2193-1801-3-542

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© Longenecker et al.; licensee Springer. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Time-dependent changes of prepulse induced suppression of the acoustic startle response in mice for a 360 day duration after sound exposure. (A) Changes of prepulse detection performance in a single mouse. Open bars represent mean ± SD of ratios measured before sound exposure. Grey and black bars represent the ratios which were (black bars) or were not (grey bars) significantly different from the control. (B) The histogram depicts only significant increases in the ratios as a function of background frequency obtained from a sample of 12 sound-exposed mice.