Figure 4. The relation between cell area and nuclear projected area during trypsin mediated deadhesion.
(a, b) Changes in cell spreading and nuclear projected area (normalized values) as a function of time, obtained from individual cells (different symbols). Normalization is done using the formula
. (c) Variation in nuclear projected area as a function of cell spreading for the same cells. The line is the same fit as in Fig. 1b, and is plotted for comparison. In some cases nuclear area shows an undershoot where the area decreases below the final value as seen in (b). Moreover, in some cases cell shrinkage precedes nuclear shrinkage as can be seen in (c).
