Table 3.

Visual analogue scale assessments (mm) of pain, numbness and groin discomfort at the 12-month post-operative visit: ITT population and patients with pre-operative PND (at least one VAS >30 mm)

	ITT population			Patients experiencing pre-operative PND (at least one VAS >30 mm)
	Tisseel/Tissucol N = 149	Sutures N = 150	p value	Tisseel/Tissucol N = 60	Sutures N = 62	p value
Pain
Mean ± SD	3.9 ± 11.5	5.9 ± 14.8	0.113	6.6 ± 14.6	10.7 ± 19.3	0.195
Median (range)	0 (0–76)	0 (0–90)		0 (0–76)	0 (0–90)
Interquartile range	0–0	0–0		0–5	0–15
Numbness
Mean ± SD	4.1 ± 10.6	7.4 ± 14.6	0.019*	3.4 ± 8.6	11.0 ± 19.7	0.008*
Median (range)	0 (0–91)	0 (0–100)		0 (0–50)	0 (0–100)
Interquartile range	0–0	0–10		0–0	0–19
Groin discomfort
Mean ± SD	7.1 ± 14.6	10.2 ± 16.8	0.049*	9.0 ± 14.6	17.3 ± 21.5	0.018*
Median (range)	0 (0–75)	0 (0–80)		0 (0–50)	7.5 (0–80)
Interquartile range	0–10	0–20		0–18	0–25

ITT intention-to-treat, PND pain, numbness and pain discomfort, SD standard deviation, VAS visual analogue scale

* p < 0.05 for Tisseel versus suture subgroup, non-parametric mixed covariance analysis