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. 2014 Sep 21;14:344. doi: 10.1186/1472-6882-14-344

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© Yim et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Anti-proliferative effect of GBT on human cancer cells. Cell viability was determined by MTT assay. The results are expressed as percentages of viable cells compared to untreated cells (vehicle). Data show the means ± SD of two independent triplicate experiments. (A) Inhibition of cell viability by GBT in several human cancer cell lines for 48 h. (B) Comparison of the effects of GBT on the viability of three squamous carcinoma cell lines: A431, SCC12, and SCC13 for 48 h. (C) Effect of GBT on the growth of A431 and HaCaT cells for 24 and 48 h, respectively. (D) Comparison of GBT-induced cytotoxicity between A431 cells and mouse primary liver cells (as a normal cells) in a dose- and time-dependent manner.