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. 2014 Sep 21;14:344. doi: 10.1186/1472-6882-14-344

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© Yim et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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In vivo anti-tumor activity of GBT. The A431 cells were injected into anthymic nude mice and treated daily with either vehicle or 600 mg/Kg for 14 days, which was terminated at the end of 15 days. The results show the significant reduction of tumors by GBT. (A) Tumor growth inhibition by GBT. (B) Changes in body weight during the administration of GBT. (C, D) Comparision of anti-tumor activity between vehicle and GBT according the representive tumor images and the measurement of tumor weight. Data shown are mean ± SD, ^* P < 0.05 versus vehicle.