Table 3.

List of metabolic pathway databases

Link of the databases	Teams or specificity	Numbers of metabolites	Data included
BioCyc ( http://humancyc.org/)	Pathway/Genome database	371 pathways	Tier 1: metabolites, enzymes activators/inhibitors and cofactors; Tier 2 and Tier 3: computationally predicted pathways and gene codes.
HumanCyc ( http://biocyc.org/)	Bioinformatics database	28,783 genes	Metabolic pathways and the human genome
KEGG ( http://www.genome.jp/kegg/)	Kyoto Encyclopedia of Genes and Genomes	372 reference pathways, >15,000 compounds, 7,742 drugs and ~11,000 glycan structures	Metabolic pathways hyperlinked to metabolite and protein/enzyme information
Metacyc ( http://metacyc.org/)	Data base of nonredundant, experimentally elucidated metabolic pathways	More than 1,100 pathways of more than 1,500 different organisms	Pathways of both primary and secondary metabolisms as well as associated compounds, enzymes, and genes
Reactome ( http://www.reactome.org/)	A curated, peer-reviewed knowledge base of biological pathways	More than 2,700 proteins, 2,800 reactions and 860 pathways for humans	Metabolic pathways, protein trafficking and signal pathways