Figure 7.

Supernatant of tumor pretreated with EGFR inhibitor modulated T cell responses toward peptide stimulation. EGFR_875–889-reactive CD4⁺ T cell clone T8 and M8 were tested for their capacity to recognize 3 μg/ml peptide pulsed-autologous PBMC with or without supernatant of Calu-1 or 5637 tumor cells culture and anti-TGF-β antibody (10 μg) by measuring of IFN-γ production. Columns without bars had SD of <10% of mean values. Results are representative of three separate experiments. *p < 0.05.