Figure 1.

Chromosomal segments showing the conserved syntenic blocks containing muscle miRNAs in fishes. The genes are represented by colored pentagons and its name is indicated on top. Color pentagons indicate the same gene in different species (right) and its respective genomic position in relation to several other genes. White pentagons indicate absence of the gene in genome. The pentagon’s direction indicates the gene direction (sense or anti-sense) compared to the reference gene. The empty spaces indicate a region with other genes or repetitive elements. (A) miR-1-1/-133a2, in this case we used zebrafish as reference since none syntenic regions were encountered in this cluster within Nile tilapia genome; (B) miR-1-2/-133a-1 and its host gene Mib1; (C) miR-206/-133b; (D) miR-499 and its host gene Myh7b, in this case we used pentagons with white circles to indicate non-intronic miRNA; (E) miR-214 and its host gene Dnm3; (F) miR-214-par and its host gene Dnm3.