Table 1.
Demographic and biochemical parameters among normal, non-diabetic obese and non-obese type 2 diabetes mellitus groups
| Parameters | Normal (n = 31) | Non-diabetic obese (n = 30) | Non-obese T2DM (n = 31) |
|---|---|---|---|
| Age (years) | 31.3 (27.8-35.2) | 28.4 (26.6-32.4) | 45.2 (39.8-51.3) |
| p-value | a0.44 | a 4.5 × 10 -5, b 4.0 × 10 -5 | |
| BMI (kg/m 2 ) | 20.6 (19.7-21.5) | 34.0 (32.5-35.5) | 22.3 (21.1-23.7) |
| p-value | a 5.1 × 10 -9 | a0.53, b 5.1 × 10 -9 | |
| Waist circumference (cm) | 75.1 (72.7-77.6) | 90.2 (88.0-92.5) | 71.3 (69.2-73.5) |
| p-value | a 5.1 × 10 -9 | a 0.037, b 5.1 × 10 -9 | |
| DBP (mmHg) | 75.5 (72.5-78.7) | 85.2 (82.8-87.6) | 83.5 (79.8-87.3) |
| p-value | a 4.9 × 10 -5 | a 0.00096, b0.74 | |
| SBP (mmHg) | 113 (109–117) | 126 (123–130) | 123 (116–130) |
| p-value | a 2.3 × 10 -4 | a 0.009 , b0.56 | |
| Triglyceride (mmol/l) | 1.5 (1.2-1.8) | 2.1 (2.0-2.2) | 2.0 (1.8-2.2) |
| p-value | a 0.0009 | a 0.005, b0.88 | |
| HDL-c (mmol/l) | 0.9 (0.8-1.0) | 0.8 (0.7-0.9) | 0.7 (0.6- 0.8) |
| p-value | a0.23 | a 0.01, b0.34 | |
| FBG (mmol/l) | 5.4 (5.1-5.8) | 5.7 (5.5-6.0) | 9.7 (8.3-11.4) |
| p-value | a0.66 | a 5.1 × 10 -9 , b 5.2 × 10 -9 | |
| Insulin (pmol/l) | 44.5 (37.2-53.2) | 130 (112–151) | 70.1 (54.3-90.5) |
| p-value | a 5.1 × 10 -9 | a 0.004, 5.9 × 10 -5 | |
| HOMA-β | 73.2 (62.3-85.9) | 135 (119–154) | 33.7 (23.0-49.2) |
| p-value | a 0.0007, | a 3.2 × 10 -5 , b 5.1 × 10 -9 | |
| Insulin Sensitivity (%) | 118 (99–142) | 40.8 (35.2- 47.3) | 62.4 (49.0-79.3) |
| p-value | a 5.1 × 10 -9 | a 1.6 × 10 -5 , 0.006 | |
| HOMA-IR | 0.9 (0.7-1.1) | 2.5 (2.2-2.9) | 1.7 (1.3-2.2) |
| p-value | a 5.1 × 10 -9 | a 4.9 × 10 -5 , 0.005 |
Result presented as geometric mean and 95% confidence interval of mean; avs. normal group; bvs. non-diabetic obese group evaluated by ANOVA.