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The mSMART risk stratification system in active myeloma [6].
| High risk | Intermediate risk | Standard risk |
|---|---|---|
| FISH | FISH | FISH |
| del(17p) | t(4;14) | t(4;14) |
| t(14;16) | t(6;14) | |
| t(14;20) | ||
| GEP | Cytogenetic del(13) | All other patients |
| High-risk signature | ||
| Hypodiploidy | ||
| Plasma cell labelling index ≥3% |
