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RAG model categories.
| RAG category | Initiation/primary event | Progression/secondary event |
|---|---|---|
| Hyperdiploidy (Trisomies—1, 3, 5, 7, 9, 11, 15, 19, 21) |
✓ | |
| t(4;14) | ✓ | |
| t(6;14) | ✓ | |
| t(11;14) | ✓ | |
| t(14;16) | ✓ | |
| t(14;20) | ✓ | |
| +1q | ✓ | |
| Del(1p) | ✓ | |
| Del(11q) | ✓ | |
| Del(12p) | ✓ | |
| Del(13/13q) | ✓ | |
| Del(14q) | ✓ | |
| Del(16q) | ✓ | |
| Del(17p) | ✓ | |
| Secondary t(8;14) | ✓ | |
| Bone disease | ✓ | |
| Proliferation | ✓ | |
| Apoptosis and NF-κB | ✓ | |
| Differentiation | ✓ | |
| DNA repair | ✓ | |
| RNA editing | ✓ | |
| Epigenetic | ✓ |
